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POLB 抗体 (C-Term)

Name: POLB 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN964928
Availability: OutOfStock

POLB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western Blot of Rabbit anti-POLB antibody. (POLB 抗体 (C-Term))

Western Blot of Rabbit Anti-POLß (DNA polymerase beta) Antibody (). (POLB 抗体 (C-Term))

2 images

(2 references)

产品编号 ABIN964928

发货至: 中国

Datasheet as PDF

抗原 See all POLB 抗体

POLB (Polymerase (DNA Directed), beta (POLB))
抗原表位
15

5

4

3

3

1

1

1

1

1

1

1

1

1
C-Term
适用
43

41

27

10

3

2

2

2

2

2

2

1

1

1

1
人
宿主
53

3
兔
Compatible Secondaries
克隆类型
46

9
多克隆
标记
24

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This POLB antibody is un-conjugated
应用范围
34

16

16

14

13

8

4

3

2

1
Western Blotting (WB), ELISA

特异性

This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with overexpressed and endogenous POLß protein. A BLAST analysis was used to suggest reactivity with POLß from human, bovine, and Xenopus laevis based on a 100% homology with the immunizing sequence. Cross-reactivity with POLß from other sources has not been determined.

产品特性

The POLß protein belongs to the DNA polymerase type-X family. It is a DNA polymerase involved in gap-filling DNA synthesis or base excision and repair in a stepwise distributive fashion unlike other DNA polymerases. It is required for DNA maintenance, replication, recombination, and drug resistance. It is normally found as a monomer, in the cytoplasm and it translocates to the nucleus upon DNA damage.

纯化方法

affinity purified

过滤

Sterile filtered

免疫原

This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptidecorresponding to a region near the C-terminus of the POLß protein.
Immunogen Type: Peptide

亚型

IgG

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anti-Polymerase (DNA Directed), beta (POLB) (AA 1-335) antibody
POLB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 1-335) antibody
POLB 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibody
POLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 1-300) antibody
POLB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 55-160) antibody
POLB 适用: 小鼠 WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibody
POLB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibody
POLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 224-333) antibody
POLB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 1-335) antibody
POLB 适用: 人 IP 宿主: 兔 Polyclonal unconjugated

anti-Polymerase (DNA Directed), beta (POLB) (AA 107-156) antibody
POLB 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 山羊, 豚鼠, 马, 兔, Hamster, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

This affinity purified antibody is suitable for ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 38.1 kDa in size corresponding to POLß by western blotting in the appropriate cell lysate or extract.

说明

Gene Name: POLB

限制

仅限研究用
状态

Liquid

浓度

1.4 mg/mL

缓冲液

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

有效期

12 months
Asagoshi, Liu, Masaoka, Lan, Prasad, Horton, Brown, Wang, Bdour, Sobol, Taylor, Yasui, Wilson: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).

Sobol, Foley, Nyska, Davidson, Wilson: "Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice." in: DNA repair, Vol. 2, Issue 5, pp. 609-22, (2004) (PubMed).
抗原

POLB (Polymerase (DNA Directed), beta (POLB))

别名

POLB (POLB 产品)

别名

wu:fa97a05 antibody, zgc:109924 antibody, POLB antibody, DDBDRAFT_0186152 antibody, DDBDRAFT_0215784 antibody, DDBDRAFT_0232376 antibody, DDB_0186152 antibody, DDB_0215784 antibody, DDB_0232376 antibody, A430088C08Rik antibody, polymerase (DNA directed), beta antibody, DNA polymerase beta antibody, DNA polymerase X family protein antibody, polymerase (DNA directed), beta S homeolog antibody, polb antibody, POLB antibody, polB antibody, polb.S antibody, Polb antibody

背景

The POLß protein belongs to the DNA polymerase type-X family. It is a DNA polymerase involved in gap-filling DNA synthesis or base excision and repair in a stepwise distributive fashion unlike other DNA polymerases. It is required for DNA maintenance, replication, recombination, and drug resistance. It is normally found as a monomer, in the cytoplasm and it translocates to the nucleus upon DNA damage.
Synonyms: DNA polymerase beta, POLB, beta-pol

基因ID

5423

NCBI登录号

NP_002681

UniProt

P06746

途径

DNA Damage Repair