UBASH3B 抗体 (C-Term)
(2 references)-
- 抗原 See all UBASH3B (STS1) 抗体
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBASH3B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 过滤
- Sterile filtered
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the of mouse Sts-1.
- 亚型
- IgG
- Top Product
- Discover our top product STS1 Primary Antibody
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anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibody
STS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-441) antibodySTS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibodySTS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 564-613) antibodySTS1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-442) antibodySTS1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.63 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2." in: Immunity, Vol. 20, Issue 1, pp. 37-46, (2004) (PubMed).
: "Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7491-500, (2002) (PubMed).
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: "Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2." in: Immunity, Vol. 20, Issue 1, pp. 37-46, (2004) (PubMed).
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- 抗原
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
- 别名
- Sts-1 (STS1 产品)
- 别名
- STS-1 antibody, STS1 antibody, TULA-2 antibody, p70 antibody, 2810457I06Rik antibody, BB125008 antibody, RGD1310357 antibody, Sts-1 antibody, ubiquitin associated and SH3 domain containing B antibody, ubiquitin associated and SH3 domain containing, B antibody, UBASH3B antibody, Ubash3b antibody
- 背景
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Sts-1 is a protein that inhibits endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. Sts-1 and Sts-2 (formerly p70 and Clip4, respectively) have been found to interact with Cbl, an ubiquitin ligase that plays a critical role in attenuation of receptor tyrosine kinase signaling by inducing ubiquitination and promoting their sorting for endosomal degradation. Sts-1 and Sts-2 contain SH3 domains that interact with Cbl, Ub-associated domains, which bind directly to mono-Ub or to the EGFR/Ub chimera, as well as phosphoglycerate mutase domains that mediate oligomerization of Sts-1/2. Sts-1 and Sts-2 also have been found to negatively regulate signaling pathways that control T cell receptors, which in turn affect the extent and duration of the T cell response to foreign pathogens.
Synonyms: Cbl interacting protein p70 antibody, Cbl interacting protein Sts 1 antibody, Nm23 phosphorylated unknown substrate antibody, p70 antibody, SH3 domain containing 70 kDa protein antibody - 基因ID
- 84959, 24497612
- UniProt
- Q8TF42
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