UBASH3B 抗体 (C-Term)
(2 references)
-
- 抗原 See all UBASH3B (STS1) 抗体
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This UBASH3B antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-870
- Supplier
- Rockland
- 原理
- Sts-1 Antibody
- 交叉反应 （详细）
- This affinity purified antibody is directed against mouse Sts-1 protein.
- 产品特性
- Synonyms: rabbit anti-Sts-1 antibody, Sts1, Sts 1, Ubiquitin-associated and SH3 domain-containing protein B, Cbl interacting protein p70 antibody, Suppressor of T-cell receptor signaling 1, T-cell ubiquitin ligand 2, TULA-2, Tyrosine-protein phosphatase STS1/TULA2, Ubash3B
- 纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
- 过滤
- Sterile filtered
- 免疫原
-
Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus of mouse Sts-1.
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product STS1 Primary Antibody
-
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibody
STS1 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-441) antibodySTS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 1-300) antibodySTS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) antibodySTS1 适用: 人, 小鼠, 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 564-613) antibodySTS1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cbl-Interacting Protein Sts-1 (STS1) (AA 344-442) antibodySTS1 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
-
- 应用备注
-
Immunohistochemistry Dilution: 4 μg/mL
Application Note: This affinity purified antibody has been tested for use in ELISA, IHC, and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:2,000 - 1:10,000
IF Microscopy Dilution: User Optimized
Other: User Optimized
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.63 mg/mL
- 缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
-
-
: "Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2." in: Immunity, Vol. 20, Issue 1, pp. 37-46, (2004) (PubMed).
: "Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7491-500, (2002) (PubMed).
-
: "Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2." in: Immunity, Vol. 20, Issue 1, pp. 37-46, (2004) (PubMed).
-
- 抗原
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
- 别名
- UBASH3B (STS1 产品)
- 背景
- Background: Sts-1 is a protein that inhibits endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. Sts-1 and Sts-2 (formerly p70 and Clip4, respectively) have been found to interact with Cbl, an ubiquitin ligase that plays a critical role in attenuation of receptor tyrosine kinase signaling by inducing ubiquitination and promoting their sorting for endosomal degradation. Sts-1 and Sts-2 contain SH3 domains that interact with Cbl, Ub-associated domains, which bind directly to mono-Ub or to the EGFR/Ub chimera, as well as phosphoglycerate mutase domains that mediate oligomerization of Sts-1/2. Sts-1 and Sts-2 also have been found to negatively regulate signaling pathways that control T cell receptors, which in turn affect the extent and duration of the T cell response to foreign pathogens.
- 基因ID
- 84959, 24497612
- UniProt
- Q8TF42
-
