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CCL4 抗体

CCL4 适用: Pig WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN964800
Supplier Product No.: 214-401-b85
发货至: 中国
  • 抗原 See all CCL4 抗体
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    适用
    • 63
    • 43
    • 17
    • 8
    • 6
    • 6
    • 1
    • 1
    Pig
    宿主
    • 92
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 95
    • 10
    多克隆
    标记
    • 52
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CCL4 antibody is un-conjugated
    应用范围
    • 84
    • 46
    • 26
    • 14
    • 13
    • 13
    • 13
    • 11
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    • 6
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    Western Blotting (WB), ELISA
    Supplier Product No.
    214-401-b85
    Supplier
    Rockland
    原理
    MIP-1 beta Antibody
    交叉反应 (详细)
    This antibody is specific for swine CCL4 protein.
    产品特性
    Synonyms: rabbit anti-MIP 1 beta Antibody, rabbit anti-MIP-1b Antibody, rabbit anti-CCL4 antibody, CCL4, C-C motif chemokine 4, Small-inducible cytokine A4, Macrophage inflammatory protein 1-beta, MIP-1-beta, ACT-2, MIP-1ß
    纯化方法
    This product was Protein-A purified from monospecific antiserum by chromatography.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant protein raised in yeast, corresponding to the 69 amino acids of the mature swine CCL4/MIP1ß protein.

    Immunogen Type: Recombinant Protein

    亚型
    IgG
    Top Product
    Discover our top product CCL4 Primary Antibody
  • 应用备注

    Application Note: This protein-A purified MIP-1ß antibody has been tested by western blot and is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7.8 kDa in size corresponding to swine CCL4 protein by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500

    ELISA Dilution: >1:5,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C upon receipt. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    别名
    CCL4 (CCL4 产品)
    背景
    Background: In many species, both C-C chemokines macrophage inflammatory protein, or MIP-1 alpha (CCL3L1), and MIP-1 beta (CCL4) are structurally and functionally related CC chemokines. They are both potent chemoattractants for monocytes, which form an important component of the stroma of tumor tissue, and in humans may regulate tumor growth and associated inflammation. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. Both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes, but their effect on lymphocytes differ. MIP-1 alpha selectively attracts CD8+ lymphocytes, while MIP-1 beta selectively attracts CD4+ lymphocytes. They contain the four highly conserved cysteine residues present in CC chemokines. MIP-1 beta (CCL4) has specificity for CCR5 receptors. In humans, it is also a major HIV-suppressive factor produced by CD8+ T cells.
    基因ID
    396668
    UniProt
    Q711P4
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