IL-33 抗体
(1 reference)-
- 抗原 See all IL-33 (IL33) 抗体
- IL-33 (IL33) (Interleukin 33 (IL33))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-33 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA)
- 特异性
- This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-33 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
- 产品特性
- IL-33 (also known as Interleukin-33, Interleukin-1 family member 11, IL-1F11, nuclear factor from high endothelial venules and NF-HEV) is a cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 induces T helper type 2-associated cytokines. IL-33 is a secreted cytokine that is expressed at high levels in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes and is almost undetectable in placenta. The 31 kDa precursor is proteolytically converted to an 18 kDa mature form by CASP1. Anti-IL-33 antibody is ideal for investigators involved in Cardiovascular and Immunology research.
- 纯化方法
- purified
- 免疫原
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This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-33 protein.
Immunogen Type: RecombinantProtein - 亚型
- IgG
- Top Product
- Discover our top product IL33 Primary Antibody
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anti-Interleukin 33 (IL33) (AA 112-270) antibody
IL33 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, ELISA, IHC, IP, Func 宿主: 小鼠 Monoclonal IL33305B unconjugated
anti-Interleukin 33 (IL33) (AA 110-261) antibodyIL33 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Interleukin 33 (IL33) (AA 185-264) antibodyIL33 适用: 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 171-269) antibodyIL33 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Interleukin 33 (IL33) (AA 102-264) antibodyIL33 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC (p), EIA, Func 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibody (Biotin)IL33 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
anti-Interleukin 33 (IL33) (AA 1-111) antibodyIL33 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method. By western blot a band approximately 18 kDa in size corresponding to mature human IL-32α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
- 说明
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Gene Name: IL33
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Without preservative
- 储存条件
- 4 °C
- 储存方法
- Store vial at 4° C before opening. DO NOT FREEZE. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use. Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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: "Mature interleukin-33 is produced by calpain-mediated cleavage in vivo." in: Biochemical and biophysical research communications, Vol. 387, Issue 1, pp. 218-22, (2009) (PubMed).
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: "Mature interleukin-33 is produced by calpain-mediated cleavage in vivo." in: Biochemical and biophysical research communications, Vol. 387, Issue 1, pp. 218-22, (2009) (PubMed).
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- 抗原
- IL-33 (IL33) (Interleukin 33 (IL33))
- 别名
- IL-33 (IL33 产品)
- 别名
- IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
- 背景
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IL-33 (also known as Interleukin-33, Interleukin-1 family member 11, IL-1F11, nuclear factor from high endothelial venules and NF-HEV) is a cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 induces T helper type 2-associated cytokines. IL-33 is a secreted cytokine that is expressed at high levels in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes and is almost undetectable in placenta. The 31 kDa precursor is proteolytically converted to an 18 kDa mature form by CASP1. Anti-IL-33 antibody is ideal for investigators involved in Cardiovascular and Immunology research.
Synonyms: Interleukin-33, Interleukin-1 family member 11, IL-1F11, nuclear factor from high endothelial venules and NF-HEV - 基因ID
- 90865, 15559209
- UniProt
- O95760
- 途径
- Production of Molecular Mediator of Immune Response
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