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Interleukin 17a 抗体

Rockland 209-401-b32 IL17A 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN964747
Supplier Product No.: 209-401-b32
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
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    宿主
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    克隆类型
    • 67
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    多克隆
    标记
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    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 70
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    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Supplier Product No.
    209-401-b32
    Supplier
    Rockland
    原理
    IL-17A Antibody
    交叉反应 (详细)
    In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-17A in cell supernatants and certain body fluids.
    产品特性
    Synonyms: rabbit anti-Interleukin-17A antibody, rabbit anti-IL-17A antibody, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8, Interleukin-17, IL17, IL-17, Interleukin17
    纯化方法
    Anti-IL-17 Antibody was affinity purified from monospecific antiserum by Protein A Purification.
    免疫原

    Immunogen: IL-17A Antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL17-A protein.

    Immunogen Type: Recombinant Protein

    亚型
    IgG
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 1:100

    Application Note: Il-17A antibody has been tested for use in IHC and western blotting and is suitable in ELISA. By western blot a band approximately ~17.5 kDa in size corresponding to human IL17-A protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:500 - 1:2,000

    ELISA Dilution: 1:1,000 - 1:5,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    6 months
  • Shin, Shin, Noh: "Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes." in: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1835-44, (2009) (PubMed).

  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL17A (IL17A 产品)
    背景
    Background: IL17-A (also known as Interleukin-17) is a pro-inflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in cytokines, growth factors, cancer, and Immunology research.
    基因ID
    3605
    UniProt
    Q16552
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