CTCF 抗体 (C-Term)
(1 reference)-
- 抗原 See all CTCF 抗体
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTCF antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with endogenous CTCF protein. A BLAST analysis was used to suggest reactivity with CTCF from human, mouse, horse, bovine, panda, rabbit, Danio, and chicken based on a 100% homology with the immunizing sequence. Cross-reactivity with CTCF from other sources has not been determined.
- 交叉反应
- 小鼠
- 产品特性
- Transcriptional repressor CTCF (also known as CCCTC-binding factor) is a transcription factor encoded by the CTCF gene. The CTCF, and the closely related Brother of the Regulator of Imprinted Sites (BORIS), are highly conserved zinc finger proteins implicated in diverse regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. Expression of BORIS is restricted to spermatocytes and is mutually exclusive of CTCF expression. CTCF is ubiquitously expressed in higher eukaryotes and contains a highly conserved and eleven zinc finger central DNA-binding domain, having very high homology between mouse, chicken, and human and is embedded within slightly divergent N and C termini. CTFC plays a critical role in the epigenetic regulation and chromatin remodeling. CTCF has been reported to bind to a variety of DNA target sites that perform distinct functions, including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting.
- 纯化方法
- affinity purified
- 过滤
- Sterile filtered
- 免疫原
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This affinity purified antibody was prepared by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminus of CTCF protein.
Immunogen Type: Peptide - 亚型
- IgG
- Top Product
- Discover our top product CTCF Primary Antibody
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anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibody
CTCF 适用: 人 WB, IHC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人 WB, ChIP-seq, CUT&RUN 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人, 小鼠, 大鼠, 猴 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人 WB, IF, ChIP, IP 宿主: 兔 Monoclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (C-Term) antibodyCTCF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibodyCTCF 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 334-364) antibodyCTCF 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53773 unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (N-Term) antibodyCTCF 适用: 人 WB, IHC, IF, ChIP, ICC, ChIP-seq, SSA, CUT&Tag 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (N-Term) antibodyCTCF 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 马, 豚鼠, Bat, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 521-727) antibodyCTCF 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- CTCF antibody is suitable for ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 82.8 kDa or 150 kDa in size corresponding to CTCF by western blotting in the appropriate cell lysate or extract.
- 说明
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Gene Name: CTCF
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.3 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).
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: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).
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- 抗原
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
- 别名
- CTCF (CTCF 产品)
- 别名
- im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
- 背景
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Transcriptional repressor CTCF (also known as CCCTC-binding factor) is a transcription factor encoded by the CTCF gene. The CTCF, and the closely related Brother of the Regulator of Imprinted Sites (BORIS), are highly conserved zinc finger proteins implicated in diverse regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. Expression of BORIS is restricted to spermatocytes and is mutually exclusive of CTCF expression. CTCF is ubiquitously expressed in higher eukaryotes and contains a highly conserved and eleven zinc finger central DNA-binding domain, having very high homology between mouse, chicken, and human and is embedded within slightly divergent N and C termini. CTFC plays a critical role in the epigenetic regulation and chromatin remodeling. CTCF has been reported to bind to a variety of DNA target sites that perform distinct functions, including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting.
Synonyms: Transcriptional repressor CTCF, 11-zinc finger protein, CCCTC-binding factor, CTCFL paralog - 基因ID
- 10664
- NCBI登录号
- NP_006556
- UniProt
- P49711
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