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CASZ1 抗体 (Internal Region)

Rockland 600-401-b62 CASZ1 适用: 人 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN964598
Supplier Product No.: 600-401-b62
发货至: 中国
  • 抗原 See all CASZ1 抗体
    CASZ1 (Castor Zinc Finger 1 (CASZ1))
    抗原表位
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Internal Region
    适用
    • 29
    • 15
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CASZ1 antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    Supplier Product No.
    600-401-b62
    Supplier
    Rockland
    原理
    CASZ1 Antibody
    交叉反应 (详细)
    This affinity purified antibody is directed against human CASZ1 protein.
    产品特性
    Synonyms: rabbit anti-CASZ1 Antibody, CASZ1, Zinc finger protein castor homolog 1, Castor-related protein, Zinc finger protein 693, CST, SRG, ZNF693
    纯化方法
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Human Casz1 protein.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
  • 应用备注

    Immunohistochemistry Dilution: User Optimized

    Application Note: This antibody has been tested for use in ELISA, IHC, IF, and western blotting. This antiserum detects endogenous CASZ1 proteins, both the hCASZ5 and hCASZ11 isoforms. Expect a band approximately 125 kDa for hCASZ5 and 190 kDa for hCASZ11 in size corresponding CASZ1 by western blotting in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:1,000 - 1:5,000

    ELISA Dilution: 1:45,000

    IF Microscopy Dilution: User Optimized

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.09 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • Lunde, Okaty, Dymecki, Glover: "Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups." in: eNeuro, Vol. 6, Issue 1, (2019) (PubMed).

    Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

  • 抗原
    CASZ1 (Castor Zinc Finger 1 (CASZ1))
    别名
    CASZ1 (CASZ1 产品)
    背景
    Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. The human castor zinc finger 1 gene (CASZ1) regulates the production of the castor transcription factor, having increased expression when cells of neural and mesenchymal origin are induced to differentiation. CASZ1 is expressed in a number of human tumors and it localizes to a genomic region frequently lost in tumors of neuroectodermal origin. The CASZ1 gene generates 2 mRNA isoforms hCASZ5 and hCASZ11 that could encode proteins containing 5 or 11 zinc finger motifs, respectively. The proteins may be especially labile. Expect a band at 125 kDa for hCASZ5 and 190 kDa for hCASZ11 in fresh lysates.
    基因ID
    54897, 145207289
    UniProt
    Q86V15
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