Uromodulin 抗体 (HRP)
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- 抗原 See all Uromodulin (UMOD) 抗体
- Uromodulin (UMOD)
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适用
- 人, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Uromodulin antibody is conjugated to HRP
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)
- 特异性
- Anti-Human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. This monoclonal antibody has shown good localization to the distal tubule and collecting duct as well as to large deposits of Tamm-Horsfall protein which has clogged peri-pelvic veins. This antibody has been tested against 21 different Human proteins in Solid Phase Radioimmunoassay and has been shown to be specific for Tamm-Horsfall protein only. Results of ELISA show no visible reaction with Human albumin or transferrin. Also no staining of Human tissue other than that noted for kidney sections has been observed.
- 交叉反应 (详细)
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Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human. - 纯化方法
- Protein G Chromatography.
- 免疫原
- Human Tamm-Horsfall protein.
- 克隆位点
- 01-10-32
- 亚型
- IgG2b
- Top Product
- Discover our top product UMOD Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 50 % Glycerol (v/v)., 4-5 mg/mL BSA
- 注意事项
- Avoid exposure of conjugate to Sodium Azide or Thimerosal, as these can inhibit peroxidase activity.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted at (in aliquots) at -20 °C. This product is photosensitive and should be protected from light.
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- 抗原
- Uromodulin (UMOD)
- Abstract
- UMOD 产品
- 别名
- ADMCKD2 antibody, FJHN antibody, HNFJ antibody, HNFJ1 antibody, MCKD2 antibody, THGP antibody, THP antibody, urehr4 antibody, uromodulin antibody, UMOD antibody, Umod antibody
- 背景
- Tamm-Horsfall Protein (THP) is a glycoprotein of approximately 80 kDa containing up to 25 % carbohydrate by weight. It exists as a high molecular weight polymer in urine and approximately 50 mg of the THP are excreted per day by adult humans. THP is produced by the epithelial cells lining the thick ascending loop of Henle and distal convoluted tubules of the kidney. THP is also the primary constituent of renal tubular casts and THP aggregation has been implicated as a factor in the pathogenesis of acute renal failure by causing tubular obstruction. Antibody to THP is present in the serum of patients with pyelonephritis and reflus uropathy.Synonyms: THP, Tamm-Horsfall urinary glycoprotein
- 基因ID
- 7369
- NCBI登录号
- NP_001008390
- UniProt
- P07911
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