TFAM 抗体 (C-Term)
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Quick Overview for TFAM 抗体 (C-Term) (ABIN955168)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 223-254, C-Term
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特异性
- This antibody detects TFAM (C-term).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM / TCF6
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背景
- This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.Synonyms: Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6L2, Transcription factor 6, Transcription factor 6-like 2, mitochondrial Transcription factor A
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基因ID
- 7019
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NCBI登录号
- NP_003192
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途径
- Chromatin Binding
抗原
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