SITAC antibody, SITAC18 antibody, ST-2 antibody, syndecan binding protein 2 antibody, syndecan binding protein (syntenin) 2 antibody, suppression of tumorigenicity 2 antibody, SDCBP2 antibody, Sdcbp2 antibody, ST2 antibody
背景
Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.Synonyms: SITAC18, Syndecan-binding protein 2