tloc1 antibody, TLOC1 antibody, wu:fb57b06 antibody, zgc:114073 antibody, Dtrp1 antibody, HTP1 antibody, TP-1 antibody, 3100002M17Rik antibody, AI844545 antibody, AW545092 antibody, Tloc1 antibody, Ab2-292 antibody, SEC62 homolog, preprotein translocation factor S homeolog antibody, SEC62 homolog, preprotein translocation factor antibody, membrane unit of ER protein translocation apparatus antibody, SEC62 homolog (S. cerevisiae) antibody, sec62.S antibody, SEC62 antibody, sec62 antibody, Sec62 antibody
背景
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.Synonyms: Translocation protein 1, Translocation protein SEC62