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SAR1B 抗体 (Middle Region)

SAR1B 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN954670
发货至: 中国
  • 抗原 See all SAR1B 抗体
    SAR1B (SAR1 Homolog B (SAR1B))
    抗原表位
    • 10
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 96-124, Middle Region
    适用
    • 33
    • 16
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 31
    • 2
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SAR1B antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 18
    • 12
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes SAR1B (Center).
    纯化方法
    Protein A column followed by peptide Affinity purification
    免疫原
    KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of Human SAR1B Genename: SAR1B
    亚型
    Ig Fraction
    Top Product
    Discover our top product SAR1B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SAR1B (SAR1 Homolog B (SAR1B))
    别名
    SAR1B (SAR1B 产品)
    别名
    SAR1 antibody, SAR1B antibody, SARA2 antibody, 2310075M17Rik antibody, 2900019I22Rik antibody, CMRD antibody, Sara1b antibody, Sara2 antibody, Sarb antibody, cmrd antibody, gtbpb antibody, sar1a antibody, sara2 antibody, SARA1B antibody, ANDD antibody, GTBPB antibody, zgc:73204 antibody, secretion associated Ras related GTPase 1B antibody, hypothetical protein antibody, SAR1 homolog B (S. cerevisiae) antibody, secretion associated, Ras related GTPase 1B L homeolog antibody, secretion associated, Ras related GTPase 1B antibody, SAR1B antibody, Sar1B antibody, sar1b antibody, Sar1b antibody, sar1b.L antibody
    背景
    SAR1B belongs to the small GTPase superfamily, SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus and is activated by the guanine nucleotide exchange factor PREB. SAR1B is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Defects in SAR1B are the cause of chylomicron retention disease (CMRD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The conditions are characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets. Cellular localization: Endoplasmic reticulum membrane, Peripheral membrane protein. Golgi apparatus, Golgi stack membrane, Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.Synonyms: GTBPB, GTP-binding protein SAR1b, SAR1B, SARA2, SARB
    基因ID
    51128
    NCBI登录号
    NP_001028675
    途径
    Lipid Metabolism
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