Prothrombin 抗体 (Biotin)
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- 抗原 See all Prothrombin (F2) 抗体
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Prothrombin antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific for Human Prothrombin (CaPro-20).
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 免疫原
- Human Prothrombin (CaPro-20) purified from plasma.
- 克隆位点
- CaPro-20
- 亚型
- IgG1
- Top Product
- Discover our top product F2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- 别名
- Prothrombin (F2) (F2 产品)
- 别名
- PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, zgc:66319 antibody, wu:fb57c10 antibody, wu:fd42e09 antibody, wu:fd59d01 antibody, prothrombin antibody, F2 antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, coagulation factor II (thrombin) antibody, F2 antibody, f2 antibody
- 背景
- Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia. Prothrombin is a 72 kDa blood clotting glycoprotein formed by and stored in the Liver. Prothrombin is present in the blood plasma and is converted to the key blood clotting agent thrombin, when blood vessels are damaged. Factor VII, another important haemostasis protein can be converted to VIIa by Factor IXa or Thrombin.Synonyms: Coagulation factor II
- 基因ID
- 2147
- NCBI登录号
- NP_000497
- UniProt
- P00734
- 途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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