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NEDD4-2 抗体 (Middle Region)
NEDD4L
适用: 人, 小鼠
WB, EIA
宿主: 兔
Polyclonal
unconjugated
NEDD4-2抗体详情
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抗原
See all NEDD4-2 (NEDD4L) 抗体
NEDD4-2 (NEDD4L)
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
抗原表位
All epitopes for NEDD4-2 抗体
AA 575-604, Middle Region
适用
All reactivities for NEDD4-2 抗体
人, 小鼠
宿主
All hosts for NEDD4-2 抗体
兔
克隆类型
All clonalities for NEDD4-2 抗体
多克隆
标记
All conjugates for NEDD4-2 抗体
This NEDD4-2 antibody is un-conjugated
应用范围
All applications for NEDD4-2 抗体
Western Blotting (WB), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes Human and Mouse NEDD4L (Center).
纯化方法
Protein A column, followed by peptide affinity purification
免疫原
KLH conjugated synthetic peptide between 575-604 amino acids from the Central region of human NEDD4L
亚型
Ig Fraction
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Discover our top product NEDD4L Primary Antibody
Alternatives
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anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 431-480) antibody
NEDD4L
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
NEDD4-2目标详情
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抗原
NEDD4-2 (NEDD4L)
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
别名
NEDD4L (NEDD4L 产品 )
别名
NEDD4-2 antibody, NEDD4.2 antibody, RSP5 antibody, hNEDD4-2 antibody, nedd4 antibody, nedd4-2 antibody, NEDD4 antibody, Nedd4-2 antibody, 1300012C07Rik antibody, Nedd4b antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase antibody, NEDD4L antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog antibody, neural precursor cell expressed, developmentally down-regulated gene 4-like antibody, NEDD4L antibody, LOC776799 antibody, nedd4l.S antibody, Nedd4l antibody
背景
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK.Synonyms: KIAA0439, NEDD4.2, NEDL3, Nedd4-2
分子量
111932 Da
基因ID
23327
NCBI登录号
NP_001138436
途径
Negative Regulation of Transporter Activity
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