Myeloid Lineage 抗体 (FITC)
适用: 大鼠
FACS, IHC (fro), WB
宿主: 小鼠
Monoclonal
OX-82
FITC
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- 抗原
- Myeloid Lineage
- 适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- FITC
- 应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
- 交叉反应 （详细）
- Species reactivity (tested):Rat.
- 纯化方法
- Protein G Chromatography of Ascites fluid.
- 免疫原
- Anemic Rat bone marrow.
- 克隆位点
- OX-82
- 亚型
- IgG1
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anti-Myeloid Lineage antibody
适用: 大鼠 FACS, IHC (fro), WB 宿主: 小鼠 Monoclonal OX-82 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) at -20 °C for longer.
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- 抗原
- Myeloid Lineage
- 背景
- Hematopoietic stem cells (HSC) are the precursor cells found in the bone marrow which give rise to all the blood cell types of both the Myeloid and lymphoid lineages, which include monocytes and macrophages, neutrophils, basophils, eosinophils, T cells, B cells, NK cells, microglia, erythrocytes, megakaryocytes and dendritic cells. During the process of hematopoiesis, Myeloid lineage cells originate from the bone marrow, while Lymphoid lineage cells originate from the lymph tissue. Blimp-1 is a key regulator of the differentiation of the separate hematopoietic myeloid and lymphoid lineages. The distinction between myeloid and lymphoid lineages is essential to diagnose and treat certain cancers. Myeloid lineage cells induce inflammatory cytokine production upon activation by Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein. At the stage of myelocytes, Myeloid lineage cells express a substantial number of IL-8 receptor homologs.
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