This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found, however, their full-length nature is not known.Synonyms: EC=6.1.1.4, KIAA1352, LARS, LeuRS, Leucine-tRNA ligase, Leucyl-tRNA synthetase, cytoplasmic