4631408O11Rik antibody, 5430408M01Rik antibody, E130106B02 antibody, ITI-HC5 antibody, inter-alpha (globulin) inhibitor H5 antibody, inter-alpha-trypsin inhibitor heavy chain family member 5 antibody, Itih5 antibody, ITIH5 antibody
背景
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.Synonyms: Inter-alpha-trypsin inhibitor heavy chain H5, KIAA1953