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GNAS 抗体 (C-Term)

Name: GNAS 抗体 (C-Term)
SKU: ABIN952563
Availability: OutOfStock

This anti-GNAS antibody is a 兔多克隆 antibody detecting GNAS in WB, IF, FACS, IHC (p) 和 EIA. Suitable for 人.

Western blot analysis of GNAS (arrow) using GNAS Antibody (C-term) Cat. (GNAS 抗体 (C-Term))

Flow cytometric analysis of 293 cells using GNAS Antibody (C-term) Cat. (GNAS 抗体 (C-Term))

FACS

Confocal immunofluorescent analysis of GNAS Antibody (C-term) Cat. (GNAS 抗体 (C-Term))

Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue reacted with GNAS Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. (GNAS 抗体 (C-Term))

IHC (p)

Western blot analysis of GNAS Antibody (C-term) in 293, NCI-H292 cell line lysates (35ug/lane). (GNAS 抗体 (C-Term))

5 images

产品编号 ABIN952563

发货至: 中国

Datasheet as PDF

Quick Overview for GNAS 抗体 (C-Term) (ABIN952563)

抗原

See all GNAS 抗体

GNAS (GNAS Complex Locus (GNAS))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GNAS antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Discover our top product GNAS Primary Antibody

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AA 286-315, C-Term

纯化方法

Protein A column, followed by peptide affinity purification

免疫原

KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of Human GNAS

亚型

Ig Fraction
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) antibody
KO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 310-404) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (Internal Region) antibody
Verified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS containing 0.09 % (W/V) Sodium Azide as preservative

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

GNAS (GNAS Complex Locus (GNAS))

别名

GNAS

背景

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.

分子量

44,250 Da

基因ID

9606

途径

Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis