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GCLC 抗体 (N-Term)
GCLC
适用: 人
WB, IF, FACS, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
GCLC抗体详情
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抗原
See all GCLC 抗体
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
抗原表位
All epitopes for GCLC 抗体
AA 6-34, N-Term
适用
All reactivities for GCLC 抗体
人
宿主
All hosts for GCLC 抗体
兔
克隆类型
All clonalities for GCLC 抗体
多克隆
标记
All conjugates for GCLC 抗体
This GCLC antibody is un-conjugated
应用范围
All applications for GCLC 抗体
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes Human GCL / GLCLC (N-term).
纯化方法
Protein A column, followed by peptide affinity purification
免疫原
KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of Human GCLC / GLCLC
亚型
Ig Fraction
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Discover our top product GCLC Primary Antibody
Alternatives
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anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibody
GCLC
适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 犬, 豚鼠, 马
WB, IHC
宿主: 兔
Polyclonal
unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) antibody
GCLC
适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 犬, 豚鼠, 马, Saccharomyces cerevisiae
WB, IHC
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
GCLC目标详情
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抗原
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
别名
GCLC / GLCLC (GCLC 产品 )
别名
GCLC antibody, gclc antibody, MGC146287 antibody, 2259 antibody, CG2259 antibody, DmGCLC antibody, DmGCS antibody, DmGCSh antibody, Dmel\\CG2259 antibody, GCL antibody, GCLc antibody, GCSh antibody, Gcs antibody, Gcsh antibody, DDBDRAFT_0186120 antibody, DDBDRAFT_0231403 antibody, DDB_0186120 antibody, DDB_0231403 antibody, GCS antibody, GLCL antibody, GLCLC antibody, D9Wsu168e antibody, GLCL-H antibody, Ggcs-hs antibody, Glclc antibody, cb1049 antibody, fe36e11 antibody, wu:fe36e11 antibody, glutamate-cysteine ligase catalytic subunit antibody, glutamate-cysteine ligase, catalytic subunit antibody, Glutamate-cysteine ligase catalytic subunit antibody, gamma glutamylcysteine synthetase antibody, glutamate-cysteine ligase, catalytic subunit L homeolog antibody, glutamate-cysteine ligase, catalytic subunit S homeolog antibody, gamma-glutamylcysteine synthetase antibody, GCLC antibody, gclc antibody, Gclc antibody, LbGCS antibody, gcsA antibody, gclc.L antibody, gclc.S antibody, GSH1 antibody
背景
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.Synonyms: GCS heavy chain, GLCL, GLCLC, Gamma-ECS, Gamma-glutamylcysteine synthetase, Glutamate-cysteine ligase catalytic subunit
分子量
72766 Da
基因ID
2729
NCBI登录号
NP_001184044
途径
Cell RedoxHomeostasis
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