5930433H21Rik antibody, GRB2 associated binding protein 3 antibody, growth factor receptor bound protein 2-associated protein 3 antibody, GAB3 antibody, gab3 antibody, Gab3 antibody
背景
GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: GRB2-associated binder 3, GRB2-associated-binding protein 3, Growth factor receptor bound protein 2-associated protein 3