FBLIM1 antibody, CAL antibody, FBLP-1 antibody, FBLP1 antibody, 2410043F08Rik antibody, Cal antibody, Fblp1 antibody, Gt10 antibody, migfilin antibody, migfilin(s) antibody, filamin binding LIM protein 1 antibody, filamin binding LIM protein 1 S homeolog antibody, FBLIM1 antibody, fblim1.S antibody, Fblim1 antibody
背景
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: FBLP-1, FBLP1, Filamin-binding LIM protein 1, MIG2-interacting protein, Migfilin, Mitogen-inducible 2-interacting protein