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CPT1C 抗体 (C-Term)

CPT1C 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951689
发货至: 中国
  • 抗原 See all CPT1C 抗体
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 759-790, C-Term
    适用
    • 49
    • 6
    • 3
    宿主
    • 50
    • 1
    • 1
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 20
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPT1C antibody is un-conjugated
    应用范围
    • 37
    • 27
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to CPT1C.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 759-790 amino acids from the C-terminal region of human CPT1C
    亚型
    Ig Fraction
    Top Product
    Discover our top product CPT1C Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    别名
    CPT1C / CPT1-B (CPT1C 产品)
    背景
    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.Synonyms: CPT IC, Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1C, brain isoform
    分子量
    90989 Da
    基因ID
    126129
    NCBI登录号
    NP_001129524
    途径
    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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