Mrcl antibody, MRCL antibody, MRCL1 antibody, MRLP2 antibody, RGD1559899 antibody, Clec18a antibody, C-type lectin domain family 18, member A antibody, C-type lectin domain family 18 member A antibody, Clec18a antibody, LOC100385790 antibody, LOC100474931 antibody, CLEC18A antibody, LOC100717379 antibody
背景
The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-18 (C-type lectin domain family 18) exists as three nearly identical forms, designated CLEC-18A, CLEC-18B and CLEC-18C, or mannose receptor-like protein 1, 2 and 3, respectively. Both CLEC-18A and CLEC-18C contain 446 amino acids, whereas CLEC-18B contains 455 amino acids, all three forms are secreted proteins that contain one C-type lectin domain, a SCP domain and a single EGF-like domain. All three CLEC-18 proteins exist as two alternatively spliced isoforms that are encoded by genes that map to human chromosome 16q22.Synonyms: C-type lectin domain family 18 member A, MRLP2, Mannose receptor-like protein 2