CD80 抗体
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- 抗原 See all CD80 抗体
- CD80
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD80 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognises the murine CD80 cell surface protein, also known as B7-1.
- 交叉反应 (详细)
- Species reactivity (tested):Mouse.
- 纯化方法
- Purified
- 克隆位点
- RMMP-1
- 亚型
- IgG2a
- Top Product
- Discover our top product CD80 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and EIA grade BSA to bring total protein concentration to 4-5 mg/mL
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CD80
- 别名
- CD80 (CD80 产品)
- 背景
- CD80 is a member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
- 基因ID
- 12519
- NCBI登录号
- NP_033985
- UniProt
- Q00609
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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