CTLA4 抗体 (N-Term)
-
- 抗原 See all CTLA4 抗体
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
-
抗原表位
- AA 57-86, N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CTLA4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes Human CD152 / CTLA4 (N-term).
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide between 57-86 amino acids from the N-terminal region of Human CD152 / CTLA4. Genename: CTLA4
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CTLA4 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease." in: Cancer immunology, immunotherapy : CII, Vol. 67, Issue 8, pp. 1297-1303, (2018) (PubMed).
: "Prognostic impact of immune microenvironment in laryngeal and pharyngeal squamous cell carcinoma: Immune cell subtypes, immuno-suppressive pathways and clinicopathologic characteristics." in: Oncotarget, Vol. 8, Issue 12, pp. 19310-19322, (2017) (PubMed).
: "
-
Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease." in: Cancer immunology, immunotherapy : CII, Vol. 67, Issue 8, pp. 1297-1303, (2018) (PubMed).
-
- 抗原
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- 别名
- CD152 / CTLA4 (CTLA4 产品)
- 背景
- CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
- 分子量
- 24656 Da
- 基因ID
- 1493
- NCBI登录号
- NP_001032720
- 途径
- Cancer Immune Checkpoints
-