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CADM1 抗体 (Internal Region)
CADM1
适用: 人, 小鼠, 大鼠, Cow, 犬, Pig
WB, EIA
宿主: 山羊
Polyclonal
unconjugated
CADM1抗体详情
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抗原
See all CADM1 抗体
CADM1
(Cell Adhesion Molecule 1 (CADM1))
抗原表位
All epitopes for CADM1 抗体
Internal Region
适用
All reactivities for CADM1 抗体
人, 小鼠, 大鼠, Cow, 犬, Pig
宿主
All hosts for CADM1 抗体
山羊
克隆类型
All clonalities for CADM1 抗体
多克隆
标记
All conjugates for CADM1 抗体
This CADM1 antibody is un-conjugated
应用范围
All applications for CADM1 抗体
Western Blotting (WB), Enzyme Immunoassay (EIA)
序列
C-QLYTDPPQES YTT
特异性
This antibody is expected to recognize both reported isoforms (NP_055148.3, NP_001091987.1).
交叉反应 (详细)
Species reactivity (expected):Human, Rat, Dog, Pig, Cow. Species reactivity (tested):Mouse.
纯化方法
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
免疫原
Peptide with sequence from the internal region of the protein sequence according to NP_055148.3, NP_001091987.1. Genename: CADM1
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
CADM1目标详情
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抗原
CADM1
(Cell Adhesion Molecule 1 (CADM1))
别名
CADM1 / SYNCAM (CADM1 产品 )
别名
BL2 antibody, IGSF4 antibody, IGSF4A antibody, NECL2 antibody, Necl-2 antibody, RA175 antibody, ST17 antibody, SYNCAM antibody, TSLC1 antibody, sTSLC-1 antibody, sgIGSF antibody, synCAM1 antibody, bl2 antibody, igsf4 antibody, igsf4a antibody, necl-2 antibody, necl2 antibody, ra175 antibody, sgigsf antibody, st17 antibody, stslc-1 antibody, syncam antibody, syncam1 antibody, tslc1 antibody, xnecl2 antibody, 2900073G06Rik antibody, 3100001I08Rik antibody, AI987920 antibody, Bl2 antibody, Igsf4 antibody, Igsf4a antibody, Necl2 antibody, RA175A antibody, RA175B antibody, RA175C antibody, RA175N antibody, SgIGSF antibody, SynCam antibody, Tslc1 antibody, SynCAM1 antibody, cell adhesion molecule 1 antibody, cell adhesion molecule 1 L homeolog antibody, CADM1 antibody, cadm1.L antibody, Cadm1 antibody
背景
Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with binding with other cells or with the extracellular matrix. SynCAM belongs to immunoglobulin superfamily 4 and is involved in cell-cell adhesion. Loss of SynCAM is common in a number of cancers including lung, breast, prostate and meningioma. This loss of SynCAM in advanced stage cancers suggests a role in tumor invasion and/or metastasis. Also recent studies have shown that SynCAM suppresses induction of EMT (epithelial mesenchymal transition) via regulation of Rho GTPases.Synonyms: Cell adhesion molecule 1, IGSF4, IGSF4A, IgSF4, Immunoglobulin superfamily member 4, NECL-2, NECL2, Nectin-like protein 2, SgIgSF, Spermatogenic immunoglobulin superfamily, Synaptic cell adhesion molecule, TSLC-1, TSLC1, Tumor suppressor in lung cancer 1
基因ID
23705
NCBI登录号
NP_001091987
途径
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cell-Cell Junction Organization , Activated T Cell Proliferation
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