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ASXL1 抗体 (AA 521-549)

ASXL1 适用: 人, 小鼠 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN950543
发货至: 中国
  • 抗原 See all ASXL1 抗体
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    抗原表位
    • 8
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 521-549
    适用
    • 27
    • 25
    • 1
    人, 小鼠
    宿主
    • 29
    • 3
    克隆类型
    • 29
    • 3
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASXL1 antibody is un-conjugated
    应用范围
    • 22
    • 16
    • 14
    • 13
    • 13
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ASXL1 at Center.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ASXL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    别名
    ASXL1 (ASXL1 产品)
    别名
    asxl1 antibody, MGC83850 antibody, mKIAA0978 antibody, BOPS antibody, MDS antibody, additional sex combs like 1, transcriptional regulator L homeolog antibody, additional sex combs like 1, transcriptional regulator antibody, additional sex combs like 1 antibody, asxl1.L antibody, ASXL1 antibody, asxl1 antibody, Asxl1 antibody
    背景
    This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.Synonyms: Additional sex combs-like protein 1, KIAA0978, Putative Polycomb group protein ASXL1
    分子量
    165432 Da
    基因ID
    171023
    NCBI登录号
    NP_056153
    途径
    Retinoic Acid Receptor Signaling Pathway
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