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CDK1 抗体

CDK1 适用: 人, Cow, Non-Human Primate WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal POH-1 unconjugated
产品编号 ABIN94446
发货至: 中国
  • 抗原 See all CDK1 抗体
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    适用
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    人, Cow, Non-Human Primate
    宿主
    • 270
    • 59
    小鼠
    克隆类型
    • 260
    • 69
    单克隆
    标记
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    This CDK1 antibody is un-conjugated
    应用范围
    • 263
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    特异性
    The antibody POH-1 specifically detects Cdk1 (p34Cdc2, an intracellular antigen). Staining of Cdk1 reflects the proliferating potential of respective tissue.
    无交叉反应
    Drosophila melanogaster, 小鼠, 大鼠, 非洲爪蟾
    交叉反应 (详细)
    Human, Non-Human Primates, Bovine
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Bacterially expressed full-length human Cdk1 protein
    克隆位点
    POH-1
    亚型
    IgG2a
    Top Product
    Discover our top product CDK1 Primary Antibody
  • 应用备注
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: thymus.
    Western blotting: Recommended dilution: 1-2 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Lukás, Draetta, Bartek: "Distinct forms of human CDC2 identified by novel monoclonal antibodies." in: European journal of biochemistry / FEBS, Vol. 207, Issue 1, pp. 169-76, (1992) (PubMed).

  • 抗原
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    别名
    Cdk1 (CDK1 产品)
    别名
    CDC2 antibody, CDC28A antibody, P34CDC2 antibody, Cdc2 antibody, Cdc2a antibody, p34 antibody, cdc2 antibody, wu:fc30e01 antibody, zgc:92032 antibody, PSTAIR antibody, cdc-2 antibody, cdc2-a antibody, cdc28a antibody, cdc2x1.1 antibody, p34cdc2 antibody, xcdc2 antibody, 5363 antibody, CDCDm antibody, CDK1 antibody, CDK1/CDC2 antibody, CG5363 antibody, Cdk-1 antibody, Cdk1 antibody, Dcdc2 antibody, Dm cdc2 antibody, DmCdc2 antibody, DmCdk1 antibody, Dmcdc2 antibody, Dmel\\CG5363 antibody, cdc antibody, cdc2Dm antibody, cdk1 antibody, dCdk1 antibody, group 4 antibody, l(2)31Eh antibody, CDC2A antibody, CDC2AAT antibody, CDK2 antibody, CDKA1 antibody, CDKA;1 antibody, CYCLIN-DEPENDENT KINASE A;1 antibody, cell division control 2 antibody, cdc2-b antibody, cdc2a antibody, cdc2x1.2 antibody, POL3 antibody, pold antibody, cyclin dependent kinase 1 antibody, cyclin dependent kinase like 1 antibody, Cell division control protein 2 1 antibody, cyclin-dependent kinase 1 antibody, cyclin-dependent kinase 1 S homeolog antibody, Cyclin-dependent kinase 1 antibody, cell division control 2 antibody, cell division control protein2 homolog antibody, cyclin-dependent kinase 1 L homeolog antibody, polymerase (DNA directed), delta 1, catalytic subunit L homeolog antibody, cyclin-dependent protein kinase Cdk1/Cdc2 antibody, CDK1 antibody, CDKL1 antibody, POPTR_0004s14080g antibody, Cdk1 antibody, cdk1 antibody, cdk1.S antibody, CDC2 antibody, cdc2 antibody, cdk-1 antibody, cdk1.L antibody, pold1.L antibody
    背景
    Cyclin dependent kinase 1,Cdk1 (cyclin-dependent kinase 1), also known as p34Cdc2 (cell division control protein kinase 2) depends on cyclin A and B and is triggered by a positive feedback loop at the end of G2 phase, which is the key event that initiates mitotic entry. Destruction of cyclin B during metaphase results in inactivation of Cdk1, allowing mitotic exit and cell division. Cdk1 also contributes to the control of DNA replication. Cdk1 can be ihibited by several transcriptional targets of p53, such as p21WAF.,p34Cdc2, p34 protein kinase, CDK1, CDC2, CDC28A
    基因ID
    983
    UniProt
    B7Z3D6
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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