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CD97 抗体

CD97 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-180 unconjugated
产品编号 ABIN94252
发货至: 中国
  • 抗原 See all CD97 抗体
    CD97
    适用
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    宿主
    • 58
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    小鼠
    克隆类型
    • 61
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    单克隆
    标记
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    This CD97 antibody is un-conjugated
    应用范围
    • 43
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    PHA-activated peripheral blood cells
    克隆位点
    MEM-180
    亚型
    IgG1
    Top Product
    Discover our top product CD97 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Wobus, Vogel, Schmücking, Hamann, Aust: "N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." in: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).

  • 抗原
    CD97
    别名
    CD97 (CD97 产品)
    别名
    AA409984 antibody, TM7LN1 antibody, adhesion G protein-coupled receptor E5 antibody, Adgre5 antibody, ADGRE5 antibody
    背景
    Adhesion G protein-coupled receptor E5,CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.,TM7LN1, ADGRE5
    基因ID
    976
    UniProt
    P48960
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