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CD52 抗体

CD52 适用: 人 FACS, IHC (p) 宿主: 小鼠 Monoclonal HI186 unconjugated
产品编号 ABIN94170
发货至: 中国
  • 抗原 See all CD52 抗体
    CD52
    适用
    • 48
    • 11
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    • 1
    宿主
    • 19
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    • 1
    小鼠
    克隆类型
    • 34
    • 12
    • 3
    单克隆
    标记
    • 26
    • 7
    • 7
    • 4
    • 2
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    • 1
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    This CD52 antibody is un-conjugated
    应用范围
    • 36
    • 18
    • 16
    • 14
    • 14
    • 11
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    • 8
    • 5
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    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa extracellular glycoprotein containing a large N-linked carbohydrate moiety, mature CD52 Molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human tonsil
    克隆位点
    HI186
    亚型
    IgG2b
    Top Product
    Discover our top product CD52 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 2 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CD52
    别名
    CD52 (CD52 产品)
    别名
    CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody
    背景
    CD52 Molecule,CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.,CAMPATH-1, HE5, ESPE5
    基因ID
    1043
    UniProt
    P31358
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