CD44 抗体
(2 references)-
- 抗原 See all CD44 抗体
- CD44
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适用
- 人, 犬, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD44 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- 特异性
- The antibody MEM-263 reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.
- 交叉反应 （详细）
- Human, Porcine, Canine (Dog)
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- COS-7 cells (African Green Monkey).
- 克隆位点
- MEM-263
- 亚型
- IgG1
- Top Product
- Discover our top product CD44 Primary Antibody
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anti-CD44 (CD44) antibody
CD44 适用: 人, 小鼠 FACS, WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated
anti-CD44 (CD44) antibodyKO Validated CD44 适用: 人 WB, IF, IHC (p), IP, IHC (fro), ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 21-220) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated
anti-CD44 (CD44) (AA 346-385) antibodyCD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 148-247) antibodyCD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 36-194) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 7F4F12 unconjugated
anti-CD44 (CD44) (AA 21-259) antibodyCD44 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 1-361) antibodyCD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, Baboon, Green Monkey FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 156-3C11 unconjugated
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- 应用备注
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Flow cytometry: Recommended dilution: 4 μg/mL.
Western blotting: Recommended dilution: 2 μg/mL, 60 min on vertical incubator, positive control: Kg-1a human acute leukemia cell lysate, JURKAT human leukemia T-cell lysate, non-reducing conditions, 6 % separating gel.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: uterus, myometrium. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Characterisation of stemness and multipotency of ovine muscle-derived stem cells from various muscle sources." in: Journal of anatomy, Vol. 239, Issue 2, pp. 336-350, (2021) (PubMed).
: "Vascular wall-resident CD44+ multipotent stem cells give rise to pericytes and smooth muscle cells and contribute to new vessel maturation." in: PLoS ONE, Vol. 6, Issue 5, pp. e20540, (2011) (PubMed).
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: "Characterisation of stemness and multipotency of ovine muscle-derived stem cells from various muscle sources." in: Journal of anatomy, Vol. 239, Issue 2, pp. 336-350, (2021) (PubMed).
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- 抗原
- CD44
- 别名
- CD44 (CD44 产品)
- 别名
- CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody
- 背景
- CD44 Molecule,CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.,PGP-I, HUTCH-I, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, MC56, MIC4, INLU, LHR
- 基因ID
- 960
- UniProt
- P16070
- 途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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