CD42b 抗体
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- 抗原 See all CD42b (GP1BA) 抗体
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
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适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD42b antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- The antibody HIP1 reacts with an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c, 160 kDa), CD42b/c forms a noncovalent complex with CD42a and CD42d.
- 交叉反应 （详细）
- Human, Non-Human Primates
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Peripheral blood mononuclear cells of a patient suffering with CLL.
- 克隆位点
- HIP1
- 亚型
- IgG1
- Top Product
- Discover our top product GP1BA Primary Antibody
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anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibody
GP1BA 适用: 人 WB, FACS, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6H6H10 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-291) antibodyGP1BA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-128) antibodyGP1BA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-282) antibodyGP1BA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 1-626) antibodyGP1BA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibody (FITC)GP1BA 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal HIP1 FITC
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- 应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
- 别名
- CD42b (GP1BA 产品)
- 别名
- BDPLT1 antibody, BDPLT3 antibody, BSS antibody, CD42B antibody, CD42b-alpha antibody, DBPLT3 antibody, GP1B antibody, GPIbA antibody, VWDP antibody, GP1BA antibody, GPIba antibody, GPIbalpha antibody, glycoprotein Ib platelet alpha subunit antibody, glycoprotein Ib (platelet), alpha polypeptide antibody, glycoprotein 1b, alpha polypeptide antibody, GP1BA antibody, Gp1ba antibody
- 背景
- Glycoprotein Ib platelet subunit alpha,CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.,BSS, GP1B, VWDP, CD42B, GPIbA, BDPLT1, BDPLT3, DBPLT3
- 基因ID
- 2811
- UniProt
- P07359
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