ITGB1 抗体 (Biotin)
(2 references)-
- 抗原 See all ITGB1 抗体
- ITGB1 (Integrin beta 1 (ITGB1))
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适用
- 人, Pig, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ITGB1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- The antibody MEM-101A reacts with an extracellular epitope of CD29 (integrin beta1 chain), a 130 kDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).
- 无交叉反应
- 小鼠
- 交叉反应 （详细）
- Human, Porcine, Canine (Dog)
- 纯化方法
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- 免疫原
- Raji Burkitt's lymphoma cell line
- 克隆位点
- MEM-101A
- 亚型
- IgG1
- Top Product
- Discover our top product ITGB1 Primary Antibody
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anti-Integrin beta 1 (ITGB1) (AA 25-100) antibody
ITGB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人 WB, FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人, Pig, 犬 WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-101A unconjugated
anti-Integrin beta 1 (ITGB1) antibody (PE)ITGB1 适用: 人, Pig, 犬 FACS 宿主: 小鼠 Monoclonal MEM-101A PE
anti-Integrin beta 1 (ITGB1) (AA 297-380) antibodyITGB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人 WB, FACS, ELISA, IHC, IF 宿主: 兔 Monoclonal 32A10 unconjugated Recombinant Antibody
anti-Integrin beta 1 (ITGB1) (AA 454-714) antibodyITGB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Integrin beta 1 (ITGB1) (C-Term) antibodyITGB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: Recommended dilution: 1-2 μg/mL.
- 说明
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The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs." in: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 58, Issue 6, pp. 885-93, (2010) (PubMed).
: "Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
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: "Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs." in: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 58, Issue 6, pp. 885-93, (2010) (PubMed).
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- 抗原
- ITGB1 (Integrin beta 1 (ITGB1))
- 别名
- CD29 (ITGB1 产品)
- 别名
- CD29 antibody, FNRB antibody, GPIIA antibody, MDF2 antibody, MSK12 antibody, VLA-BETA antibody, VLAB antibody, 4633401G24Rik antibody, AA409975 antibody, AA960159 antibody, ENSMUSG00000051907 antibody, Fnrb antibody, Gm9863 antibody, gpIIa antibody, cd29 antibody, fnrb antibody, gpiia antibody, itgb1 antibody, mdf2 antibody, msk12 antibody, vla-beta antibody, vlab antibody, itgb1-a antibody, itgb1-b antibody, integrin subunit beta 1 antibody, integrin beta 1 (fibronectin receptor beta) antibody, integrin subunit beta 1 S homeolog antibody, integrin beta 1 antibody, integrin subunit beta 1 L homeolog antibody, ITGB1 antibody, Itgb1 antibody, itgb1.S antibody, LOC100009173 antibody, itgb1.L antibody
- 背景
- Integrin subunit beta 1,CD29 (beta1 integrin subunit, GPIIa) forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CD49a-f) determining the binding properties of beta1 (VLA) integrins. These integrins mediate cell adhesion to collagen, fibronectin, laminin and other extracellular matrix (ECM) components. This interaction hinders cell death, whereas disruption of anchorage to ECM leads to apoptosis. Decreased expression of most beta1 integrins correlates with acquiring multidrug resistance of tumour cells during selection in presence of antitumour drug. In platelets, translocation of intracellular pool of beta1 integrins to the plasma membrane following thrombin stimulation. These integrins are also up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue, as well as in regulating tissue damage and disease symptoms related to inflammatory bowel disease. Through a beta1 integrin-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta.,Integrin β,1 chain, ITGB1, VLAB, MDF2, FNRB, GPIIA, MSK12
- 基因ID
- 3688
- UniProt
- P05556
- 途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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