(2 references)-
- 抗原 See all CD2 抗体
- CD2
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Human peripheral T cells.
- 克隆位点
- MEM-65
- 亚型
- IgG1
- Top Product
- Discover our top product CD2 Primary Antibody
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 适用: 小鼠 FACS, WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (AA 25-140) antibodyCD2 适用: 人, 小鼠 FACS, WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3D1B4 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 PE
anti-CD2 (CD2) (AA 25-209) antibodyCD2 适用: 人 IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人, Pig, Non-Human Primate FACS, IF 宿主: 小鼠 Monoclonal LFA2-600 unconjugated
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- 应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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-
: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
: "New monoclonal antibodies to human leucocyte surface molecule CD2." in: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
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- 抗原
- CD2
- 别名
- CD2 (CD2 产品)
- 别名
- CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
- 背景
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- 基因ID
- 914
- UniProt
- P06729
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