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CD19 抗体

CD19 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal LT19 unconjugated
产品编号 ABIN94013
发货至: 中国
  • 抗原 See all CD19 抗体
    CD19 (CD19 Molecule (CD19))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD19 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The antibody LT19 reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Daudi human Burkitt lymphoma cell line
    克隆位点
    LT19
    亚型
    IgG1
    Top Product
    Discover our top product CD19 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Kayserova, Vcelakova, Stechova, Dudkova, Hromadkova, Sumnik, Kolouskova, Spisek, Sediva: "Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients." in: Clinical immunology (Orlando, Fla.), Vol. 153, Issue 1, pp. 49-55, (2014) (PubMed).

  • 抗原
    CD19 (CD19 Molecule (CD19))
    别名
    CD19 (CD19 产品)
    别名
    B4 antibody, CVID3 antibody, AW495831 antibody, CD19 antibody, CD19 molecule antibody, CD19 antigen antibody, CD19 antibody, Cd19 antibody
    背景
    CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3
    基因ID
    930
    UniProt
    P15391
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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