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- 抗原 See all SEMA7A 抗体
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SEMA7A antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- HPB-ALL human T cell line
- 克隆位点
- MEM-150
- 亚型
- IgM
- Top Product
- Discover our top product SEMA7A Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." in: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).
: "Evidence that CDw108 membrane protein bears the JMH blood group antigen." in: Transfusion, Vol. 35, Issue 7, pp. 566-70, (1995) (PubMed).
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Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." in: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).
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- 抗原
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
- 别名
- CD108 (SEMA7A 产品)
- 别名
- 2900057C09Rik antibody, CDw108 antibody, H-Sema-L antibody, M-Sema-L antibody, Semal antibody, CD108 antibody, H-SEMA-K1 antibody, JMH antibody, SEMAK1 antibody, SEMAL antibody, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antibody, semaphorin 7A (John Milton Hagen blood group) antibody, Sema7a antibody, SEMA7A antibody
- 背景
- Semaphorin 7A (John Milton Hagen blood group),CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors –, plexin C1 and beta1 integrins.,Semaphorin 7a, JMH blood group antigen, SEMAL, SEMAK1
- 基因ID
- 8482
- UniProt
- O75326
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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