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Endoglin 抗体 (FITC)

Name: Endoglin 抗体 (FITC)
Brand: antibodies-online
SKU: ABIN93940
Availability: OutOfStock

ENG 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal MEM-226 FITC

Separation of HUVEC cells stained using anti-human CD105 (MEM-226) FITC antibody (20 μL reagent per million cells in 100 μL of cell suspension, red-filled) from unstained HUVEC cells (black-dashed) in flow cytometry analysis (surface staining) of HUVEC cells. (Endoglin 抗体 (FITC))

FACS

Surface staining (mass cytometry) of hTERT cell line with anti-human CD105 () 143Nd. (Endoglin 抗体 (FITC))

FACS

Surface staining (flow cytometry) of HUVEC (human umbilical vein endothelial cells) with anti-human CD105 (MEM-226) FITC. (Endoglin 抗体 (FITC))

FACS

3 images

(2 references)

产品编号 ABIN93940

发货至: 中国

Datasheet as PDF

抗原 See all Endoglin (ENG) 抗体

Endoglin (ENG)
适用
170

70

41

17

10

3

2

1
人, 大鼠
宿主
108

84

18

1

1
小鼠
Compatible Secondaries
克隆类型
108

103

1
单克隆
标记
94

26

25

23

15

8

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Endoglin antibody is conjugated to FITC
应用范围
142

128

58

57

31

17

16

14

14

13

13

7

6

5

4

2

2

2

1

1

1

1

1
Flow Cytometry (FACS)

特异性

The antibody MEM-226 reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow, it is also present on syncytiotrophoblast on placenta throughout pregnancy.

交叉反应（详细）

Human, Rat

纯化方法

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Recombinant Vaccinia virus containing the human CD105 cDNA.

克隆位点

MEM-226

亚型

IgG2a

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ENG 适用: 人, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) antibody
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anti-Endoglin (ENG) antibody (APC)
ENG 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal MEM-226 APC

anti-Endoglin (ENG) (AA 370-430) antibody
ENG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

说明

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Barale, Dentelli, Togliatto, Trombetta, Olgasi, Scozzari, Toppino, Morino, Brizzi: "High glucose via NOX-dependent ROS generation and AKT activity promotes adipose-derived stem cell de-differentiation." in: Stem cells and development, (2012) (PubMed).

Schmidt, Achermann, Odermatt, Breymann, Mol, Genoni, Zund, Hoerstrup: "Prenatally fabricated autologous human living heart valves based on amniotic fluid derived progenitor cells as single cell source." in: Circulation, Vol. 116, Issue 11 Suppl, pp. I64-70, (2007) (PubMed).
抗原

Endoglin (ENG)

别名

CD105 (ENG 产品)

别名

ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody

背景

Endoglin,CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.,Endoglin, END, ENG, HHT1, ORW1

基因ID

2022

UniProt

P17813