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MME 抗体

Name: MME 抗体
Brand: antibodies-online
SKU: ABIN93930
Availability: OutOfStock

MME 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-78 unconjugated

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD10 (MEM-78) purified antibody (concentration in sample 1 μg/mL, GAM APC). (MME 抗体)

FACS

Surface staining of NALM-6 human pre-B cell leukemia cell line with anti-human CD10 (MEM-78) PE. (MME 抗体)

FACS

Separation of human neutrophil granulocytes (red-filled) from CD10 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD10 (MEM-78) purified antibody (concentration in sample 1 μg/mL, GAM APC). (MME 抗体)

FACS

3 images

(1 reference)

产品编号 ABIN93930

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
适用
190

44

37

3

2

2

2

2

2

1

1

1

1
人
宿主
99

96

2
小鼠
Compatible Secondaries
克隆类型
105

91

2
单克隆
标记
105

20

16

12

9

5

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
110

79

75

66

34

26

19

18

10

8

5

5

3

3

2

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP)

特异性

The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

交叉反应（详细）

Human

纯化方法

Purified by protein-A affinity chromatography.

纯度

> 95 % (by SDS-PAGE)

免疫原

NALM-6 human pre-B cell line

克隆位点

MEM-78

亚型

IgG1

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anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
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anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry: Recommended dilution: 1 μg/mL.

限制

仅限研究用
浓度

1 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.

储存条件

4 °C

储存方法

Store at 2-8°C. Do not freeze.
Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

CD10 (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

背景

Membrane metalloendopeptidase,CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.,CALLA, Neprilysin, Neutral endopeptidase, Enkephalinase, Atriopeptidase, MME

基因ID

4311

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration