NSD1
适用: 人, 小鼠, 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
Optimal conditions should be determined by the investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
NSD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
抗原
NSD1
(Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
NSD1 antibody, sto antibody, kmt3b antibody, sotos antibody, ara267 antibody, ARA267 antibody, KMT3B antibody, SOTOS antibody, SOTOS1 antibody, STO antibody, AI528500 antibody, nuclear receptor binding SET domain protein 1 antibody, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antibody, nuclear receptor-binding SET-domain protein 1 antibody, NSD1 antibody, nsd1 antibody, Nsd1 antibody, LOC540197 antibody
背景
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98 kDa on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Monoclonal NSD1 antibody, Anti-NSD1 antibody, Nuclear receptor binding SET domain protein 1 antibody, STO antibody, KMT3B antibody, SOTOS antibody, ARA267 antibody, FLJ22263 antibody, FLJ44628 antibody, DKFZp666C163 antibody.