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Androgen Receptor 抗体 (AA 689-919)

AR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9D12 unconjugated
产品编号 ABIN931406
发货至: 中国
  • 抗原 See all Androgen Receptor (AR) 抗体
    Androgen Receptor (AR)
    抗原表位
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    AA 689-919
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Androgen Receptor antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    免疫原
    AR antibody was raised in Mouse using a purified recombinant fragment of AR(aa689-919) expressed in E. coli as the immunogen.
    克隆位点
    1A9D12
    亚型
    IgG1
    Top Product
    Discover our top product AR Primary Antibody
  • 应用备注
    ELISA: 1:10,000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原
    Androgen Receptor (AR)
    别名
    AR (AR 产品)
    别名
    AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
    背景
    AR functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. Synonyms: Monoclonal AR antibody, Anti-AR antibody, Androgen Receptor antibody.
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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