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TFEB 抗体

TFEB 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 319C2a unconjugated
产品编号 ABIN931190
发货至: 中国
  • 抗原 See all TFEB 抗体
    TFEB (Transcription Factor EB (TFEB))
    适用
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    宿主
    • 55
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    小鼠
    克隆类型
    • 56
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    单克隆
    标记
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    This TFEB antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB), Dot Blot (DB)
    交叉反应
    交叉反应 (详细)
    Other species not studied.
    纯化方法
    Protein G affinity chromatography
    免疫原
    TFEB antibody was raised in mouse using recombinant Human Transcription Factor Eb (Tfeb)
    克隆位点
    319C2a
    亚型
    IgG1
    Top Product
    Discover our top product TFEB Primary Antibody
  • 应用备注
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    TFEB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原
    TFEB (Transcription Factor EB (TFEB))
    别名
    TFEB (TFEB 产品)
    别名
    TFEB antibody, tcfeb antibody, MGC145796 antibody, alphatfeb antibody, ALPHATFEB antibody, BHLHE35 antibody, TCFEB antibody, Tcfeb antibody, bHLHe35 antibody, transcription factor EB antibody, TFEB antibody, tfeb antibody, Tfeb antibody
    背景
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Synonyms: Monoclonal TFEB antibody, Anti-TFEB antibody, Transcription factor EB antibody, TCFEB antibody, AlphaT antibody.
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