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TFEB 抗体

TFEB 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 319C2a unconjugated
产品编号 ABIN931190
发货至: 中国
  • 抗原 See all TFEB 抗体
    TFEB (Transcription Factor EB (TFEB))
    适用
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    宿主
    • 55
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    小鼠
    克隆类型
    • 54
    • 6
    单克隆
    标记
    • 37
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    This TFEB antibody is un-conjugated
    应用范围
    • 55
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    Western Blotting (WB), Dot Blot (DB)
    交叉反应
    交叉反应 (详细)
    Other species not studied.
    纯化方法
    Protein G affinity chromatography
    免疫原
    TFEB antibody was raised in mouse using recombinant Human Transcription Factor Eb (Tfeb)
    克隆位点
    319C2a
    亚型
    IgG1
    Top Product
    Discover our top product TFEB Primary Antibody
  • 应用备注
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    TFEB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原
    TFEB (Transcription Factor EB (TFEB))
    别名
    TFEB (TFEB 产品)
    背景
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Synonyms: Monoclonal TFEB antibody, Anti-TFEB antibody, Transcription factor EB antibody, TCFEB antibody, AlphaT antibody.
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