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CTCF 抗体

CTCF 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 252C3a unconjugated
产品编号 ABIN931147
发货至: 中国
  • 抗原 See all CTCF 抗体
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    适用
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    宿主
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    小鼠
    克隆类型
    • 37
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    单克隆
    标记
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    This CTCF antibody is un-conjugated
    应用范围
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    Immunocytochemistry (ICC), Dot Blot (DB)
    交叉反应
    交叉反应 (详细)
    Other species not studied.
    纯化方法
    Protein G affinity chromatography
    免疫原
    CTCF antibody was raised in mouse using recombinant Human Ccctc-Binding Factor (Zinc Finger Protein)
    克隆位点
    252C3a
    亚型
    IgG1
    Top Product
    Discover our top product CTCF Primary Antibody
  • 应用备注
    ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    CTCF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    别名
    CTCF (CTCF 产品)
    别名
    im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
    背景
    This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Synonyms: Monoclonal CTCF antibody, Anti-CTCF antibody, CCCTC-binding factor (zinc finger protein) antibody.
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