Optimal conditions should be determined by the investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
RHOB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
ARH6 antibody, ARHB antibody, MST081 antibody, MSTP081 antibody, RHOH6 antibody, AA017882 antibody, Arh6 antibody, Arhb antibody, RHO antibody, arha antibody, rhoa antibody, wu:fj42e08 antibody, zgc:92206 antibody, rhob antibody, xrhob antibody, ras homolog family member B antibody, ras homolog gene family, member Ab antibody, ras homolog family member B S homeolog antibody, RHOB antibody, Rhob antibody, rhoab antibody, rhob.S antibody
背景
RHOB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Synonyms: Monoclonal RHOB antibody, Anti-RHOB antibody, Ras homolog gene family member B antibody, ARH6 antibody, ARHB antibody, RHOH6 antibody, MST081 antibody, MSTP081 antibody.