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CARD8 抗体

CARD8 适用: 人 WB, ICC, IP, FACS, DB 宿主: 小鼠 Monoclonal 2108C2a unconjugated
产品编号 ABIN930979
发货至: 中国
  • 抗原 See all CARD8 抗体
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    适用
    • 38
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    宿主
    • 34
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    小鼠
    克隆类型
    • 36
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    单克隆
    标记
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    This CARD8 antibody is un-conjugated
    应用范围
    • 30
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS), Dot Blot (DB)
    交叉反应
    交叉反应 (详细)
    Other species not studied.
    纯化方法
    Protein G affinity chromatography
    免疫原
    CARD8 antibody was raised in mouse using recombinant Human Caspase Recruitment Domain Family, Member 8 (Card8)
    克隆位点
    2108C2a
    亚型
    IgG1
  • 应用备注
    WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    CARD8 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    别名
    CARD8 (CARD8 产品)
    别名
    CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody
    背景
    The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. Synonyms: Monoclonal CARD8 antibody, Anti-CARD8 antibody, Caspase recruitment domain family antibody, DACAR antibody, NDPP1 antibody, TUCAN antibody, CARDINAL antibody, KIAA0955 antibody,MGC57162 antibody, DKFZp779L0366 antibody.
    途径
    Positive Regulation of Endopeptidase Activity
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