USP10 抗体 (C-Term)
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- 抗原 See all USP10 抗体
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 大鼠
- 纯化方法
- Purified
- 免疫原
- Usp10 antibody was raised in rabbit using the C terminal of Usp10 as the immunogen
- Top Product
- Discover our top product USP10 Primary Antibody
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- 应用备注
- Optimal conditions should be determined by the investigator.
- 说明
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Usp10 Blocking Peptide, catalog no. 33R-7850, is also available for use as a blocking control in assays to test for specificity of this Usp10 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
- 别名
- Usp10 (USP10 产品)
- 背景
- Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Synonyms: Polyclonal Usp10 antibody, Anti-Usp10 antibody, ubiquitin specific peptidase 10 antibody, MGC124997 antibody.
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