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USP10 抗体 (C-Term)

USP10 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN929190
发货至: 中国
  • 抗原 See all USP10 抗体
    USP10 (Ubiquitin Specific Peptidase 10 (USP10))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 70
    • 26
    • 24
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 62
    • 8
    克隆类型
    • 54
    • 16
    多克隆
    标记
    • 36
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP10 antibody is un-conjugated
    应用范围
    • 58
    • 21
    • 15
    • 14
    • 11
    • 9
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    大鼠
    纯化方法
    Purified
    免疫原
    Usp10 antibody was raised in rabbit using the C terminal of Usp10 as the immunogen
    Top Product
    Discover our top product USP10 Primary Antibody
  • 应用备注
    Optimal conditions should be determined by the investigator.
    说明

    Usp10 Blocking Peptide, catalog no. 33R-7850, is also available for use as a blocking control in assays to test for specificity of this Usp10 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    USP10 (Ubiquitin Specific Peptidase 10 (USP10))
    别名
    Usp10 (USP10 产品)
    别名
    T4F9.30 antibody, T4F9_30 antibody, ubiquitin-specific protease 9 antibody, ubpo antibody, USP10 antibody, id:ibd1190 antibody, wu:fc19h08 antibody, wu:fc76g05 antibody, wu:fi11g01 antibody, UBPO antibody, 2610014N07Rik antibody, Uchrp antibody, mKIAA0190 antibody, usp10-A antibody, ubiquitin specific peptidase 10 antibody, universal stress protein UspA antibody, ubiquitin-specific protease 9 antibody, ubiquitin carboxyl-terminal hydrolase 10 antibody, ubiquitin specific peptidase 10 S homeolog antibody, USP10 antibody, RR_RS14970 antibody, UBP9 antibody, PTRG_07201 antibody, MGYG_06403 antibody, usp10 antibody, Usp10 antibody, usp10.S antibody
    背景
    Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Synonyms: Polyclonal Usp10 antibody, Anti-Usp10 antibody, ubiquitin specific peptidase 10 antibody, MGC124997 antibody.
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