USP8 抗体 (C-Term)
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- 抗原 See all USP8 抗体
- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Purified
- 免疫原
- USP8 antibody was raised in rabbit using the C terminal of USP8 as the immunogen
- Top Product
- Discover our top product USP8 Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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USP8 Blocking Peptide, catalog no. 33R-2843, is also available for use as a blocking control in assays to test for specificity of this USP8 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
- 别名
- USP8 (USP8 产品)
- 别名
- HumORF8 antibody, UBPY antibody, AI574262 antibody, AW557536 antibody, Ubpy antibody, mKIAA0055 antibody, ubiquitin carboxyl-terminal hydrolase 8 antibody, ubiquitin specific peptidase 8 antibody, LOC9310109 antibody, MGYG_00369 antibody, USP8 antibody, Usp8 antibody
- 背景
- USP8 is a hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. USP8 catalytic activity is enhanced in the M phase. USP8 is involved in cell proliferation. USP8 is required to enter into S phase in response to serum stimulation. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. USP8 probably regulates the stability of STAM2 and RASGRF1. USP8 regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. Synonyms: Polyclonal USP8 antibody, Anti-USP8 antibody, ubiquitin specific peptidase 8 antibody, FLJ34456 antibody, HumORF8 antibody, KIAA0055 antibody, MGC129718 antibody, UBPY antibody.
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