CISH 抗体 (N-Term)
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- 抗原 See all CISH 抗体
- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CISH antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 纯化方法
- Purified
- 免疫原
- Cish antibody was raised in rabbit using the N terminal of Cish as the immunogen
- Top Product
- Discover our top product CISH Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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Cish Blocking Peptide, catalog no. 33R-7890, is also available for use as a blocking control in assays to test for specificity of this Cish antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
- 别名
- Cish (CISH 产品)
- 别名
- CISH antibody, cis antibody, cish.a antibody, ptk9l antibody, twf1l antibody, wu:fk57g04 antibody, zgc:154062 antibody, zgc:91817 antibody, g18 antibody, socs antibody, cis-1 antibody, cish antibody, BACTS2 antibody, CIS antibody, CIS-1 antibody, G18 antibody, SOCS antibody, AI385595 antibody, CIS1 antibody, Cis antibody, F17 antibody, F23 antibody, cytokine inducible SH2 containing protein antibody, cytokine inducible SH2-containing protein antibody, CISH antibody, cish antibody, Cish antibody
- 背景
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Synonyms: Polyclonal Cish antibody, Anti-Cish antibody, cytokine inducible SH2-containing protein antibody, AI385595 antibody, CIS1 antibody, Cis antibody, F17 antibody, F23 antibody.
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
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