PYHIN1 抗体 (N-Term)
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- 抗原 See all PYHIN1 抗体
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PYHIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠, 牛, 犬
- 纯化方法
- Purified
- 免疫原
- PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen
- Top Product
- Discover our top product PYHIN1 Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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PYHIN1 Blocking Peptide, catalog no. 33R-1404, is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- 别名
- PYHIN1 (PYHIN1 产品)
- 别名
- IFIX antibody, RP11-520H16.1 antibody, 4930422C14 antibody, AI447904 antibody, Ifi209 antibody, Ifix antibody, pyrin and HIN domain family member 1 antibody, interferon activated gene 209 antibody, PYHIN1 antibody, Ifi209 antibody
- 背景
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.
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