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UBA3 抗体 (N-Term)

UBA3 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN928369
发货至: 中国
  • 抗原 See all UBA3 抗体
    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
    抗原表位
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 31
    • 21
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 小鸡, 非洲爪蟾
    宿主
    • 31
    克隆类型
    • 30
    • 1
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBA3 antibody is un-conjugated
    应用范围
    • 22
    • 17
    • 14
    • 4
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠, 牛, 犬, 小鸡, Frog, 斑马鱼
    纯化方法
    Purified
    免疫原
    UBA3 antibody was raised in rabbit using the N terminal of UBA3 as the immunogen
    Top Product
    Discover our top product UBA3 Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    UBA3 Blocking Peptide, catalog no. 33R-2446, is also available for use as a blocking control in assays to test for specificity of this UBA3 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
    别名
    UBA3 (UBA3 产品)
    别名
    UBE1C antibody, hUBA3 antibody, Ube1c antibody, ube1c antibody, wu:fb75e04 antibody, wu:fc37b11 antibody, zgc:55528 antibody, A830034N06Rik antibody, AI256736 antibody, AI848246 antibody, AW546539 antibody, ubiquitin like modifier activating enzyme 3 antibody, ubiquitin-like modifier activating enzyme 3 antibody, ubiquitin like modifier activating enzyme 3 S homeolog antibody, UBA3 antibody, Uba3 antibody, uba3 antibody, uba3.S antibody
    背景
    UBA3 is a catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. UBA3 down-regulates steroid receptor activity. UBA3 is necessary for cell cycle progression.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Synonyms: Polyclonal UBA3 antibody, Anti-UBA3 antibody, ubiquitin-like modifier activating enzyme 3 antibody, DKFZp566J164 antibody, MGC22384 antibody, UBE1C antibody, hUBA3 antibody.
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