MAF 抗体 (N-Term)
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- 抗原 See all MAF 抗体
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 斑马鱼, 小鸡, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠, 牛, 小鸡, 犬, 斑马鱼
- 纯化方法
- Purified
- 免疫原
- MAF antibody was raised in rabbit using the N terminal of MAF as the immunogen
- Top Product
- Discover our top product MAF Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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MAF Blocking Peptide, catalog no. 33R-5744, is also available for use as a blocking control in assays to test for specificity of this MAF antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- 别名
- MAF (MAF 产品)
- 别名
- MAF antibody, DKFZp459D1731 antibody, 2810401A20Rik antibody, A230108G15Rik antibody, AW047063 antibody, c-maf antibody, CCA4 antibody, c-MAF antibody, Maf2 antibody, cMaf antibody, Z-cmaf antibody, c-Maf antibody, fl13d12 antibody, wu:fl13d12 antibody, C-Maf antibody, MAF bZIP transcription factor antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, avian musculoaponeurotic fibrosarcoma oncogene homolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antibody, MAF antibody, Maf antibody, mafa antibody
- 背景
- MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. Synonyms: Polyclonal MAF antibody, Anti-MAF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog, avian antibody, MGC71685 antibody.
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